THE DEVELOPMENT OF NEONATAL GUT MICROBIOTA AND ITS ROLE IN HEALTH AND DISEASE

THE DEVELOPMENT OF NEONATAL GUT MICROBIOTA AND ITS ROLE IN HEALTH AND DISEASE

S. Andreica1, Romana Vulturar2,3, Adina Chis2,3, A.C. Miu3

1 Neonatology, Department 9 – Mother and Child Care, Faculty of Medicine, University of Medicine and Farmacy ”Iuliu Hatieganu” Cluj-Napoca, Romania
2 Cell and Molecular Biology, Department 3 – Molecular Sciences, Faculty of Medicine, University of Medicine and Pharmacy ”Iuliu Hatieganu” Cluj-Napoca, Romania
3 Cognitive Neuroscience Laboratory, Department of Psycology, Babes-Bolyai University, ClujNapoca, Romania

 

Abstract
The initial microbiota formation in newborns is likely to be a critical determinant in the development of certain pediatric diseases. The process is affected by many factors such as: mode of delivery, infant gestational age and postnatal age, host genetics, feeding types and nutrition, environmental factors (familial transmission), and antibiotics and/or probiotics and prebiotics use. We review hereinafter the recent knowledge of the impact of both mode of delivery and newborn diet on gut microbiota development and we also discuss the link between neonatal gut microbiota and stress-related behaviors.

 

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