07 aug. 2008 ANALGEZIA PERIDURALA LA NASTERE CU DOZE IN CONCENTRATII SCAZUTE VERSUS CONCENTRATII STANDARD
M. Lerintiu*, S. L. Angheloiu**, D. Muresan*, G. Caracostea**
*Clinica Ginecologie I, Spitalul Clinic Judetean, Cluj
**Clinica ATI, Spitalul Clinic de Adulti
Rezumat
Standardul de aur în analgesia obstetricalã implicã utilizarea de concentratii minime de analgesic local în asociere cu un opioid administrate la nivel spinal. Scopul acestui studiu este de a compara douã tipuri de analgezie la nastere realizate cu anestezic local în concentratie scãzutã la care s-a asociat un opioid.
Studiul a fost prospective, comparativ, randomizat, dublu orb. Au fost incluse în studiu 80 de gravide, randomizate în douã loturi egale: ropivacainã standard (R0.2%) n=40 si ropivacainã în concetratii scãzute (R0.1%) n=40 la care s-a asociat fentanyl 0.0002% (2microg/ml). Au fost urmãriti parametrii demografici, obtetricali, caracteristicile blocului anestezic spinal, evolutia travaliului, starea fãtului.
Abstract
An opioid can be combined with local anaesthetic to reduce the incidence of side-effects and to improve analgesia for the relief of labour pain. Epidural 0.2% ropivacaine is recommended by the manufacturer for labour analgesia, but lower concentrations may be effective. The objective of this study was to compare 0.1% ropivacaine with 0.2% ropivacaine and to examine the effect of addition of fentanyl.
A prospective, double-blinded study was performed in 80 ASA physical status I-II parturients who were divided randomly into two groups to receive either 0.1% ropivacaine with fentanyl 2 microg/ml (group R1, n=40) or 0.2% ropivacaine with fentanyl 0.2microg/ml (group R2, n=40). We recorded: patient demographics, quality of analgesia, labor characteristics, side effects, neonatal outcome.