11 ian. 2019 CHRONIC RESPIRATORY DISEASE IN PREGNANCY
D. Ona1,2, Doina Todea3, Iulia Coropetchi2, Ioana Cristina Rotar1,2,#, D. Muresan1,2
1 – 1st Department of Obstetrics and Gynecology, University of Medicine and Pharmacy “Iuliu Hatieganu”, Clinicilor 3-5, Cluj Napoca, Romania
2 – 1st Clinic of Obstetrics and Gynecology, Emergency County Hospital, Cluj Napoca, Romania
Pregnancy related modifications play an important role for the physiology of respiratory system. Therefore, chronic respiratory diseases have a different clinical presentation and management during pregnancy. The present article focuses on the particularities of the main respiratory conditions in pregnancy. The management of asthma, one of the most common chronic illnesses in pregnancy, remains largely unchanged compared to the nonpregnant state. Pregnancy does not seem to interfere with the course of sarcoidosis. Considering the risk of relapse after delivery, pregnant women with a sarcoidosis history should benefit from clinical and radiological follow-up. Molecular testing for cystic fibrosis mutations is widespread and it is the routine in reproductive decisionmaking and diagnosis. Diagnosis of tuberculosis in pregnancy may be challenging, its symptoms can be confused with those of a normal pregnancy. Moreover, the pregnancy weight gain can mask the tuberculosis associated weight loss. Rifampicin, INH and Ethambutol are the first line drugs while Pyrazinamide use in pregnancy is gaining more and more popularity. Women with obstructive sleep apnea during pregnancy may have a significantly higher risk of developing hypertensive pregnancy disorders: gestational hypertension, preeclampsia or eclampsia.
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